Biomodels second Webinar of 2014, “Preclinical Models of Lung Inflammatory Disease”

Pulmonary disease is among the leading causes of death in the United States and is responsible for more than $150 billion in healthcare costs; with increasing incidences of COPD, asthma and idiopathic pulmonary fibrosis the need to develop innovative therapeutic options for the treatment of these inflammatory lung diseases is imperative. Due to the unique mechanical nature of the lung, the interdependence of lung mechanics and pulmonary inflammation, a relevant translational model must evaluate not only the inflammation but how the underlying disease affects the mechanical properties of the lung. This webinar will showcase translational and predictive animal models of pulmonary disease that focus on both the underlying inflammatory process as well as how the degree and type of inflammation influence change in lung compliance and airway hyperactivity. Additionally, the webinar will provide an overview of each clinical condition and how the utilization of both traditional and functional analyses in our animal models result in outcomes that will best predict how your therapeutic will behave in the clinic.
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