3rd Webinar of 2014, “Immunological Methods to Enhance Translatability of Pre-clinical Models of GVHD and IBD”

Knowledge of the involvement of the innate and adaptive immune systems is relevant to the vast majority of disease models. Consequently the ability to integrate advanced immunological methods into pre-clinical models of disease markedly enhances their predictive value in the drug development process. Thus the application of flow cytometry, fluorescence- and magnetic-activated cell sorting, and adoptive transfers of immune cells have resulted in creating robust platforms from which potential interventions for immunologically-based diseases can be effectively and accurately evaluated. This webinar discusses the general application of immunological techniques to enhance the in-life and end-point analysis of existing disease models, as well as highlighting the use of specific sorted immune cells in two adoptive transfer-based models of graft versus host disease and colitis.


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